GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
Synonyms:
Species:
Human GABRA4 (2557), Mouse Gabra4 (14397), Rat Gabra4 (140675), chicken GABRA4 (422770), cow GABRA4 (282238), dog GABRA4 (482132), sheep GABRA4 (101121776), domestic cat GABRA4 (101098052), domestic guinea pig Gabra4 (100721252), naked mole-rat Gabra4 (101718327)
UniProtKB ID:
Gene ID:
- Human(2557) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
- Mouse(14397) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
- Rat(140675) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- chicken(422770) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- cow(282238) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- dog(482132) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- sheep(101121776) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic cat(101098052) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic guinea pig(100721252) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- naked mole-rat(101718327) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- Domestic Rabbit(100339882) gamma-aminobutyric acid (GABA) A receptor, alpha 4
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Small Molecule - Agonist
Product Number
Description
Species
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Lorazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GABRA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-GABA A Receptor-R-Phycoerythrin antibody produced in mouse, clone S398A-34,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S398A-34,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S398A-34,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-Atto 488 antibody produced in mouse, clone S398A-34,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human