FXYD7
FXYD domain containing ion transport regulator 7
Human FXYD7 (53822), Mouse Fxyd7 (57780), Rat Fxyd7 (63848), cow FXYD7 (616128), naked mole-rat Fxyd7 (101706549), domestic guinea pig Fxyd7 (100724180), domestic cat FXYD7 (101088634)
- Human(53822) Summary: This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Dec 2000]
- Mouse(57780) FXYD domain-containing ion transport regulator 7
- Rat(63848) FXYD domain-containing ion transport regulator 7
- cow(616128) FXYD domain containing ion transport regulator 7
- naked mole-rat(101706549) FXYD domain containing ion transport regulator 7
- domestic guinea pig(100724180) FXYD domain containing ion transport regulator 7
- domestic cat(101088634) FXYD domain containing ion transport regulator 7
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