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FXYD4

FXYD domain containing ion transport regulator 4

Synonyms:
CHIF
Species:
UniProtKB ID:
Gene ID:
  • Human(53828) Summary: This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na,K-ATPase, as has FXYD2, also known as the gamma subunit of the Na,K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, May 2010]
  • Mouse(108017) FXYD domain-containing ion transport regulator 4
  • Rat(64190) FXYD domain-containing ion transport regulator 4
  • domestic guinea pig(100733950) FXYD domain containing ion transport regulator 4
  • naked mole-rat(101720686) FXYD domain containing ion transport regulator 4
  • Horse(100050067) FXYD domain containing ion transport regulator 4
  • cow(100295639) FXYD domain containing ion transport regulator 4
  • sheep(101118499) FXYD domain containing ion transport regulator 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FXYD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FXYD4,
Species
human
MISSION® esiRNA, targeting mouse Fxyd4,
Species
mouse