FRMPD2
FERM and PDZ domain containing 2
PDZD5C, PDZK4, PDZK5C
Human FRMPD2 (143162), Domestic Rabbit FRMPD2 (100348282), chicken FRMPD2 (423777), domestic guinea pig Frmpd2 (100721411), sheep FRMPD2 (101115935), cow FRMPD2 (520665), Horse FRMPD2 (100051923), domestic cat FRMPD2 (101088029), dog FRMPD2 (486768)
- Human(143162) Summary: This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]
- Domestic Rabbit(100348282) FERM and PDZ domain containing 2
- chicken(423777) FERM and PDZ domain containing 2
- domestic guinea pig(100721411) FERM and PDZ domain containing 2
- sheep(101115935) FERM and PDZ domain containing 2
- cow(520665) FERM and PDZ domain containing 2
- Horse(100051923) FERM and PDZ domain containing 2
- domestic cat(101088029) FERM and PDZ domain containing 2
- dog(486768) FERM and PDZ domain containing 2
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Antibodies
Anti-FRMPD2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
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western blot