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FREM1

FRAS1 related extracellular matrix 1

Synonyms:
BNAR, C9orf143, C9orf145, C9orf154, MOTA, TILRR, TRIGNO2
Species:
UniProtKB ID:
Gene ID:
  • Human(158326) Summary: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011]
  • Mouse(329872) Fras1 related extracellular matrix protein 1
  • Rat(298185) Fras1 related extracellular matrix 1
  • domestic guinea pig(100721071) FRAS1 related extracellular matrix 1
  • naked mole-rat(101713531) FRAS1 related extracellular matrix 1
  • Domestic Rabbit(100340366) FRAS1 related extracellular matrix 1
  • chicken(427355) FRAS1 related extracellular matrix 1
  • domestic cat(101096177) FRAS1 related extracellular matrix 1
  • dog(481547) FRAS1 related extracellular matrix 1
  • cow(508018) FRAS1 related extracellular matrix 1
  • sheep(101121399) FRAS1 related extracellular matrix 1
  • Horse(100062297) FRAS1 related extracellular matrix 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FREM1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry

immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FREM1,
Species
human
MISSION® esiRNA, targeting mouse Frem1,
Species
mouse