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FMO2

flavin containing monooxygenase 2 (non-functional)

Synonyms:
FMO 1B1, FMO 2, FMO1B1
Species:
UniProtKB ID:
Gene ID:
  • Human(2327) Summary: The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in some human populations, this enzyme is truncated and likely degraded rapidly. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq, Jun 2013]
  • Mouse(55990) flavin containing monooxygenase 2
  • Rat(246245) flavin containing monooxygenase 2
  • domestic cat(101086867) flavin containing monooxygenase 2 (non-functional)
  • dog(480076) flavin containing monooxygenase 2 (non-functional)
  • sheep(101104842) flavin containing monooxygenase 2 (non-functional)
  • cow(504401) flavin containing monooxygenase 2 (non-functional)
  • naked mole-rat(101710590) flavin containing monooxygenase 2 (non-functional)
  • domestic guinea pig(100725320) flavin containing monooxygenase 2 (non-functional)
  • domestic guinea pig(100135520) flavin containing monooxygenase 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FMO2 Antibody, serum, from rabbit,
Species Reactivity
chimpanzee, human, mouse, orangutan
Application
immunohistochemistry
western blot
Anti-FMO2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FMO2,
Species
human