FGFRL1
fibroblast growth factor receptor-like 1
Synonyms:
FGFR5, FHFR
Species:
Human FGFRL1 (53834), Mouse Fgfrl1 (116701), Rat Fgfrl1 (360903), chicken FGFRL1 (395107), domestic cat FGFRL1 (101095654), cow FGFRL1 (532327), domestic guinea pig Fgfrl1 (100720221), dog FGFRL1 (488865), dog FGFRL1 (100505382), naked mole-rat Fgfrl1 (101724061)
UniProtKB ID:
Gene ID:
- Human(53834) Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(116701) fibroblast growth factor receptor-like 1
- Rat(360903) fibroblast growth factor receptor-like 1
- chicken(395107) fibroblast growth factor receptor-like 1
- domestic cat(101095654) fibroblast growth factor receptor-like 1
- cow(532327) fibroblast growth factor receptor-like 1
- domestic guinea pig(100720221) fibroblast growth factor receptor-like 1
- dog(488865) fibroblast growth factor receptor-like 1
- dog(100505382) fibroblast growth factor receptor-like 1
- naked mole-rat(101724061) fibroblast growth factor receptor-like 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FGFRL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence