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FBXW2

F-box and WD repeat domain containing 2

Synonyms:
FBW2, Fwd2, Md6
Species:
UniProtKB ID:
Gene ID:
  • Human(26190) Summary: F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]
  • Mouse(30050) F-box and WD-40 domain protein 2
  • Rat(311881) F-box and WD repeat domain containing 2
  • Domestic Rabbit(100339343) F-box and WD repeat domain containing 2
  • sheep(101122758) F-box and WD repeat domain containing 2
  • cow(767863) F-box and WD repeat domain containing 2
  • domestic cat(101086186) F-box and WD repeat domain containing 2
  • Horse(100067698) F-box and WD repeat domain containing 2
  • dog(610990) F-box and WD repeat domain containing 2
  • chicken(417088) F-box and WD repeat domain containing 2
  • Zebrafish(553942) F-box and WD repeat domain containing 2
  • naked mole-rat(101724545) F-box and WD repeat domain containing 2
  • domestic guinea pig(100723973) F-box and WD repeat domain containing 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FBXW2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-FBXW2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-FBXW2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FBXW2,
Species
human
MISSION® esiRNA, targeting mouse Fbxw2,
Species
mouse