ENSA
endosulfine alpha
Synonyms:
ARPP-19e
Species:
Human ENSA (2029), Mouse Ensa (56205), Rat Ensa (60334), naked mole-rat Ensa (101725556), chicken ENSA (425073), sheep ENSA (101107055), domestic guinea pig Ensa (100714626), cow ENSA (281142), dog ENSA (475837), domestic cat ENSA (101085485)
UniProtKB ID:
Gene ID:
- Human(2029) Summary: The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(56205) endosulfine alpha
- Rat(60334) endosulfine alpha
- naked mole-rat(101725556) endosulfine alpha
- chicken(425073) endosulfine alpha
- sheep(101107055) endosulfine alpha
- domestic guinea pig(100714626) endosulfine alpha
- cow(281142) endosulfine alpha
- dog(475837) endosulfine alpha
- domestic cat(101085485) endosulfine alpha
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ENSA antibody produced in mouse, clone 1H7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-ENSA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot