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EME1

essential meiotic structure-specific endonuclease 1

Synonyms:
MMS4L, SLX2A
Species:
UniProtKB ID:
Gene ID:
  • Human(146956) Summary: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
  • Mouse(268465) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • Rat(287634) essential meiotic structure-specific endonuclease 1
  • domestic guinea pig(100732469) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • Zebrafish(558350) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • naked mole-rat(101705463) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • chicken(422104) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • Horse(100056366) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • dog(491079) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • sheep(101106603) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • cow(100125299) essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • domestic cat(101091164) essential meiotic endonuclease 1 homolog 1 (S. pombe)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EME1 (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human EME1,
Species
human
MISSION® esiRNA, targeting mouse Eme1,
Species
mouse