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MilliporeSigma

EFNA5

ephrin-A5

Synonyms:
AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
Species:
UniProtKB ID:
Gene ID:
  • Human(1946) Summary: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq, Jul 2008]
  • Mouse(13640) ephrin A5
  • Rat(116683) ephrin A5
  • domestic guinea pig(100735338) ephrin-A5
  • sheep(101115792) ephrin-A5
  • chicken(396100) ephrin-A5
  • cow(616742) ephrin-A5
  • dog(608458) ephrin-A5
  • naked mole-rat(101724262) ephrin-A5

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EFNA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-EFNA5 antibody produced in mouse, clone 1A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
Ephrin-A5/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Efna5,
Species
mouse
MISSION® esiRNA, targeting human EFNA5,
Species
human