DUSP7
dual specificity phosphatase 7
Synonyms:
MKPX, PYST2
Species:
Human DUSP7 (1849), Mouse Dusp7 (235584), Rat Dusp7 (300980), naked mole-rat Dusp7 (101699953), domestic guinea pig Dusp7 (100723574), cow DUSP7 (785016), sheep DUSP7 (101112604), Zebrafish dusp7 (327246), chicken DUSP7 (415891), domestic cat DUSP7 (101101624)
UniProtKB ID:
Gene ID:
- Human(1849) Summary: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]
- Mouse(235584) dual specificity phosphatase 7
- Rat(300980) dual specificity phosphatase 7
- naked mole-rat(101699953) dual specificity phosphatase 7
- domestic guinea pig(100723574) dual specificity phosphatase 7
- cow(785016) dual specificity phosphatase 7
- sheep(101112604) dual specificity phosphatase 7
- Zebrafish(327246) dual specificity phosphatase 7
- chicken(415891) dual specificity phosphatase 7
- domestic cat(101101624) dual specificity phosphatase 7
- dog(484742) dual specificity phosphatase 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DUSP7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DUSP7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-DUSP7, (N-terminal) antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot