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DPH3

diphthamide biosynthesis 3

Synonyms:
DELGIP, DELGIP1, DESR1, DPH3A, KTI11, ZCSL2
Species:
UniProtKB ID:
Gene ID:
  • Human(285381) Summary: This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]
  • Mouse(105638) diphthamine biosynthesis 3
  • Rat(680594) diphthamide biosynthesis 3
  • domestic cat(101097089) DPH3, KTI11 homolog (S. cerevisiae)
  • cow(511579) DPH3, KTI11 homolog (S. cerevisiae)
  • dog(610533) DPH3, KTI11 homolog (S. cerevisiae)
  • Zebrafish(553692) diphthamide biosynthesis 3
  • chicken(420643) DPH3, KTI11 homolog (S. cerevisiae)
  • domestic guinea pig(100725710) diphthamide biosynthesis 3
  • naked mole-rat(101720523) DPH3, KTI11 homolog (S. cerevisiae)
  • sheep(101120039) DPH3, KTI11 homolog (S. cerevisiae)

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DPH3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Dph3,
Species
mouse
MISSION® esiRNA, targeting human DPH3,
Species
human