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DEDD

death effector domain containing

Synonyms:
CASP8IP1, DEDD1, DEFT, FLDED1
Species:
UniProtKB ID:
Gene ID:
  • Human(9191) Summary: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21945) death effector domain-containing
  • Rat(83631) death effector domain-containing
  • naked mole-rat(101707280) death effector domain containing
  • domestic guinea pig(100734796) death effector domain containing
  • sheep(101106303) death effector domain containing
  • cow(538428) death effector domain containing
  • domestic cat(101091992) death effector domain containing
  • Horse(100066256) death effector domain containing
  • dog(488649) death effector domain containing
  • chicken(425378) death effector domain containing

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-DEDD antibody produced in mouse, clone 1C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-DEDD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-Dedd Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-DEDD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DEDD,
Species
human