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CYP26A1

cytochrome P450, family 26, subfamily A, polypeptide 1

Synonyms:
CP26, CYP26, P450RAI, P450RAI1
Species:
UniProtKB ID:
Gene ID:
  • Human(1592) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(13082) cytochrome P450, family 26, subfamily a, polypeptide 1
  • Rat(154985) cytochrome P450, family 26, subfamily a, polypeptide 1
  • Zebrafish(30381) cytochrome P450, subfamily XXVIA, polypeptide 1
  • cow(539047) cytochrome P450, family 26, subfamily A, polypeptide 1
  • chicken(408183) cytochrome P450, family 26, subfamily A, polypeptide 1
  • dog(486804) cytochrome P450, family 26, subfamily A, polypeptide 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CYP26A1 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CYP26A1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-Cytochrome P450 26A1 Antibody, clone F27P6A1, clone F27P6A1, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Ketoconazole, 99.0-101.0% (EP, titration),
Species
mouse, human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cyp26a1,
Species
mouse
MISSION® esiRNA, targeting human CYP26A1,
Species
human