CRYGD
crystallin, gamma D
Synonyms:
CACA, CCA3, CCP, CRYG4, CTRCT4, PCC, cry-g-D
Species:
Human CRYGD (1421), Mouse Crygd (12967), Rat Crygd (24278), dog CRYGD (488495), domestic cat CRYGD (101092875), cow CRYGD (281723), sheep CRYGD (101106832)
UniProtKB ID:
Gene ID:
- Human(1421) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
- Mouse(12967) crystallin, gamma D
- Rat(24278) crystallin, gamma D
- dog(488495) crystallin, gamma D
- domestic cat(101092875) crystallin, gamma D
- cow(281723) crystallin, gamma D
- sheep(101106832) crystallin, gamma D
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CRYGD antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CRYGD, (C-terminal) antibody produced in mouse, clone 2H3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-CRYGD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CRYGD antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CRYGD (151-165) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
esiRNA
Product Number
Description
Species