CRYBB2
crystallin, beta B2
Synonyms:
CCA2, CRYB2, CRYB2A, CTRCT3, D22S665
Species:
Human CRYBB2 (1415), Mouse Crybb2 (12961), Rat Crybb2 (25422), domestic guinea pig Crybb2 (100306964), Zebrafish crybb2 (553182), chicken CRYBB2 (396088), dog CRYBB2 (486326), domestic cat CRYBB2 (101083214), sheep CRYBB2 (101104345), naked mole-rat Crybb2 (101709109) ...More
UniProtKB ID:
Gene ID:
- Human(1415) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts. [provided by RefSeq, Jul 2008]
- Mouse(12961) crystallin, beta B2
- Rat(25422) crystallin, beta B2
- domestic guinea pig(100306964) crystallin, beta B2
- Zebrafish(553182) crystallin, beta B2
- chicken(396088) crystallin, beta B2
- dog(486326) crystallin, beta B2
- domestic cat(101083214) crystallin, beta B2
- sheep(101104345) crystallin, beta B2
- naked mole-rat(101709109) crystallin, beta B2
- cow(287011) crystallin, beta B2
- Domestic Rabbit(100037715) crystallin, beta B2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CRYBB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species