COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
Synonyms:
COX7AL, COX7AL1, COXVIIAL, COXVIIa-L, VIIAL
Species:
Human COX7A2 (1347), Mouse Cox7a2 (12866), Rat Cox7a2 (29507), cow COX7A2 (327688), chicken COX7A2 (772260)
UniProtKB ID:
Gene ID:
- Human(1347) Summary: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]
- Mouse(12866) cytochrome c oxidase subunit VIIa 2
- Rat(29507) cytochrome c oxidase subunit VIIa polypeptide 2
- cow(327688) cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
- chicken(772260) cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-COX7S/A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot