COL25A1
collagen, type XXV, alpha 1
Synonyms:
AMY, CLAC, CLAC-P, CLACP
Species:
Human COL25A1 (84570), Mouse Col25a1 (77018), Rat Col25a1 (687064), dog COL25A1 (610442), domestic cat COL25A1 (101089352), chicken COL25A1 (429900), domestic guinea pig Col25a1 (100717264), naked mole-rat Col25a1 (101706837), Horse COL25A1 (100072894), cow COL25A1 (615661)
UniProtKB ID:
Gene ID:
- Human(84570) Summary: This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
- Mouse(77018) collagen, type XXV, alpha 1
- Rat(687064) collagen, type XXV, alpha 1
- dog(610442) collagen, type XXV, alpha 1
- domestic cat(101089352) collagen, type XXV, alpha 1
- chicken(429900) collagen, type XXV, alpha 1
- domestic guinea pig(100717264) collagen, type XXV, alpha 1
- naked mole-rat(101706837) collagen, type XXV, alpha 1
- Horse(100072894) collagen, type XXV, alpha 1
- cow(615661) collagen, type XXV, alpha 1
- sheep(101120576) collagen, type XXV, alpha 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-COL25A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human
Application
western blot
Monoclonal Anti-COL25A1 antibody produced in mouse, clone 1D2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-COL25A1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Collagen XXV α1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species