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CMBL

carboxymethylenebutenolidase homolog (Pseudomonas)

Synonyms:
JS-1
Species:
UniProtKB ID:
Gene ID:
  • Human(134147) Summary: CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]
  • Mouse(69574) carboxymethylenebutenolidase-like (Pseudomonas)
  • Rat(310201) carboxymethylenebutenolidase homolog (Pseudomonas)
  • Zebrafish(100151256) carboxymethylenebutenolidase-like (Pseudomonas)
  • chicken(420928) carboxymethylenebutenolidase homolog (Pseudomonas)
  • domestic cat(101093165) carboxymethylenebutenolidase homolog (Pseudomonas)
  • dog(478619) carboxymethylenebutenolidase homolog (Pseudomonas)
  • sheep(101121802) carboxymethylenebutenolidase homolog (Pseudomonas)
  • naked mole-rat(101723921) carboxymethylenebutenolidase homolog (Pseudomonas)
  • domestic guinea pig(100733675) carboxymethylenebutenolidase homolog (Pseudomonas)
  • cow(516405) carboxymethylenebutenolidase homolog (Pseudomonas)

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CMBL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CMBL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CMBL,
Species
human
MISSION® esiRNA, targeting mouse Cmbl,
Species
mouse