CFHR5
complement factor H-related 5
Synonyms:
CFHL5, CFHR5D, FHR-5, FHR5
Species:
Human CFHR5 (81494), Domestic Rabbit CFHR5 (100347766), dog CFHR5 (490262), cow CFHR5 (100337035), sheep CFHR5 (101122966), Horse CFHR5 (100146849)
UniProtKB ID:
Gene ID:
- Human(81494) Summary: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]
- Domestic Rabbit(100347766) complement factor H-related 5
- dog(490262) complement factor H-related 5
- cow(100337035) complement factor H-related 5
- sheep(101122966) complement factor H-related 5
- Horse(100146849) complement factor H-related 5
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Human CFHR5 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
esiRNA
Product Number
Description
Species