CA11
carbonic anhydrase XI
Synonyms:
CARPX1
Species:
Human CA11 (770), domestic guinea pig Ca11 (100730055), dog CA11 (484400), sheep CA11 (443426), cow CA11 (326334), domestic cat CA11 (101081097), naked mole-rat Ca11 (101719709)
UniProtKB ID:
Gene ID:
- Human(770) Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]
- domestic guinea pig(100730055) carbonic anhydrase XI
- dog(484400) carbonic anhydrase XI
- sheep(443426) carbonic anhydrase XI
- cow(326334) carbonic anhydrase XI
- domestic cat(101081097) carbonic anhydrase XI
- naked mole-rat(101719709) carbonic anhydrase XI
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