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BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

Synonyms:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Species:
UniProtKB ID:
Gene ID:
  • Human(701) Summary: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
  • Mouse(12236) budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
  • Rat(171576) BUB1 mitotic checkpoint serine/threonine kinase B
  • naked mole-rat(101705847) BUB1 mitotic checkpoint serine/threonine kinase B
  • domestic guinea pig(100728730) BUB1 mitotic checkpoint serine/threonine kinase B
  • sheep(101108313) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • cow(537027) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • Horse(100629735) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • domestic cat(101087670) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • dog(608350) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • chicken(378922) budding uninhibited by benzimidazoles 1 homolog beta (yeast)

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BubR1 Antibody, clone 8G1, clone 8G1, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot
Monoclonal Anti-BUB1B antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

proximity ligation assay

western blot
Monoclonal Anti-BUB1B antibody produced in mouse, clone 3F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-BUB1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-BubR1 Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
flow cytometry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
BUB1B, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BUB1B,
Species
human