BACE2
beta-site APP-cleaving enzyme 2
Synonyms:
AEPLC, ALP56, ASP1, ASP21, BAE2, CEAP1, DRAP
Species:
Human BACE2 (25825), Mouse Bace2 (56175), Rat Bace2 (288227), domestic cat BACE2 (101096756), cow BACE2 (534774), domestic guinea pig Bace2 (100720853), dog BACE2 (478418), naked mole-rat Bace2 (101717943), chicken BACE2 (418526), sheep BACE2 (101102027)
UniProtKB ID:
Gene ID:
- Human(25825) Summary: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Mouse(56175) beta-site APP-cleaving enzyme 2
- Rat(288227) beta-site APP-cleaving enzyme 2
- domestic cat(101096756) beta-site APP-cleaving enzyme 2
- cow(534774) beta-site APP-cleaving enzyme 2
- domestic guinea pig(100720853) beta-site APP-cleaving enzyme 2
- dog(478418) beta-site APP-cleaving enzyme 2
- naked mole-rat(101717943) beta-site APP-cleaving enzyme 2
- chicken(418526) beta-site APP-cleaving enzyme 2
- sheep(101102027) beta-site APP-cleaving enzyme 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BACE2 Antibody, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-BACE2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
ANTI-BACE2C(C-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot