ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
Synonyms:
ATP2B2, MXRA1, PMCA4, PMCA4b, PMCA4x
Species:
Human ATP2B4 (493), Mouse Atp2b4 (381290), Rat Atp2b4 (29600), Horse ATP2B4 (100034081), Horse ATP2B4 (100049920), domestic cat ATP2B4 (101101538), dog ATP2B4 (403731), chicken ATP2B4 (419934), Zebrafish atp2b4 (768304), naked mole-rat Atp2b4 (101699650) ...More
UniProtKB ID:
Gene ID:
- Human(493) Summary: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(381290) ATPase, Ca++ transporting, plasma membrane 4
- Rat(29600) ATPase, Ca++ transporting, plasma membrane 4
- Horse(100034081) ATPase, Ca++ transporting, plasma membrane 4
- Horse(100049920) ATPase, Ca++ transporting, plasma membrane 4
- domestic cat(101101538) ATPase, Ca++ transporting, plasma membrane 4
- dog(403731) ATPase, Ca++ transporting, plasma membrane 4
- chicken(419934) ATPase, Ca++ transporting, plasma membrane 4
- Zebrafish(768304) ATPase, Ca++ transporting, plasma membrane 4
- naked mole-rat(101699650) ATPase, Ca++ transporting, plasma membrane 4
- domestic guinea pig(100337639) ATPase, Ca++ transporting, plasma membrane 4
- Domestic Rabbit(100353865) ATPase, Ca++ transporting, plasma membrane 4
- cow(282146) ATPase, Ca++ transporting, plasma membrane 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ATP2B4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-ATP2B4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ATP2B4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-PMCA4b Antibody, clone JA3, clone JA3, from mouse,
Species Reactivity
chimpanzee, human
Application
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-pan-PMCA Antibody, clone 5F10, clone 5F10, from mouse,
Species Reactivity
chicken, human, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot