ATF6B
activating transcription factor 6 beta
Synonyms:
CREB-RP, CREBL1, G13
Species:
Human ATF6B (1388), Mouse Atf6b (12915), Rat Atf6b (406169), dog ATF6B (474855), Zebrafish atf6b (777612), naked mole-rat Atf6b (101715793), domestic guinea pig Atf6b (100726957), Domestic Rabbit ATF6B (100357489), sheep ATF6B (101113631), cow ATF6B (513928) ...More
UniProtKB ID:
Gene ID:
- Human(1388) Summary: The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- Mouse(12915) activating transcription factor 6 beta
- Rat(406169) activating transcription factor 6 beta
- dog(474855) activating transcription factor 6 beta
- Zebrafish(777612) activating transcription factor 6 beta
- naked mole-rat(101715793) activating transcription factor 6 beta
- domestic guinea pig(100726957) activating transcription factor 6 beta
- Domestic Rabbit(100357489) activating transcription factor 6 beta
- sheep(101113631) activating transcription factor 6 beta
- cow(513928) activating transcription factor 6 beta
- Horse(100059348) activating transcription factor 6 beta
- domestic cat(101094849) activating transcription factor 6 beta
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