ASB2
ankyrin repeat and SOCS box containing 2
Synonyms:
ASB-2
Species:
Human ASB2 (51676), Mouse Asb2 (65256), Rat Asb2 (299266), domestic guinea pig Asb2 (100735515), naked mole-rat Asb2 (101706168), sheep ASB2 (101114059), dog ASB2 (490836), chicken ASB2 (423428), cow ASB2 (539244), Horse ASB2 (100064381)
UniProtKB ID:
Gene ID:
- Human(51676) Summary: This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- Mouse(65256) ankyrin repeat and SOCS box-containing 2
- Rat(299266) ankyrin repeat and SOCS box-containing 2
- domestic guinea pig(100735515) ankyrin repeat and SOCS box containing 2
- naked mole-rat(101706168) ankyrin repeat and SOCS box containing 2
- sheep(101114059) ankyrin repeat and SOCS box containing 2
- dog(490836) ankyrin repeat and SOCS box containing 2
- chicken(423428) ankyrin repeat and SOCS box containing 2
- cow(539244) ankyrin repeat and SOCS box containing 2
- Horse(100064381) ankyrin repeat and SOCS box containing 2
- domestic cat(101101572) ankyrin repeat and SOCS box containing 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ASB2 antibody produced in mouse, clone 1E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA