ANTXR1
anthrax toxin receptor 1
Synonyms:
ATR, GAPO, TEM8
Species:
Human ANTXR1 (84168), Mouse Antxr1 (69538), Rat Antxr1 (362393), naked mole-rat Antxr1 (101701494), domestic guinea pig Antxr1 (100728514), sheep ANTXR1 (101108204), Domestic Rabbit ANTXR1 (100357637), cow ANTXR1 (616010), domestic cat ANTXR1 (101092930), Horse ANTXR1 (100061334) ...More
UniProtKB ID:
Gene ID:
- Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
- Mouse(69538) anthrax toxin receptor 1
- Rat(362393) anthrax toxin receptor 1
- naked mole-rat(101701494) anthrax toxin receptor 1
- domestic guinea pig(100728514) anthrax toxin receptor 1
- sheep(101108204) anthrax toxin receptor 1
- Domestic Rabbit(100357637) anthrax toxin receptor 1
- cow(616010) anthrax toxin receptor 1
- domestic cat(101092930) anthrax toxin receptor 1
- Horse(100061334) anthrax toxin receptor 1
- dog(612601) anthrax toxin receptor 1
- chicken(428199) anthrax toxin receptor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-ANTXR1-pY425 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
dot blot
dot blot
Anti-ATR (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-TEM8/Anthrax Toxin Receptor 1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Species Reactivity
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot