1133580
USP
Oversulfated Chondroitin Sulfate
United States Pharmacopeia (USP) Reference Standard
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About This Item
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
heparin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
General description
Oversulfated Chondroitin Sulfate (OSCS) is a prominent contaminant found in heparin that is connected to adverse clinical events. OSCS exhibits plasma anticoagulant activity and the capability to activate prekallikrein to kallikrein.
Oversulfated Chondroitin Sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia
Oversulfated Chondroitin Sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia
Application
Oversulfated Chondroitin Sulfate USP reference standard suitable for use in specified USP compendial tests and assays. Also used to prepare system suitability solutions for the identification of heparin sodium by proton NMR (Nuclear magnetic resonance) spectroscopy and chromatography method.
Further information is available in the monograph, Heparin Sodium, USP43-NF38 - 2195 of the USP (United States Pharmacopeia).
Further information is available in the monograph, Heparin Sodium, USP43-NF38 - 2195 of the USP (United States Pharmacopeia).
Other Notes
This product is part of the USP Biologics program.
Sales restrictions may apply.
related product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Oversulfated Chondroitin Sulfate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(6), 2195-2195 (2018)
The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system
Hogwood J, et al.
PLoS ONE (2018)
The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system
Hogwood J, et al.
Testing (2018)
Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events
Guerrini M, et al.
Nature Biotechnology (2008)
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