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About This Item
Empirical Formula (Hill Notation):
C40H73N11O11S1
Molecular Weight:
916.14
UNSPSC Code:
12352200
NACRES:
NA.32
Pricing and availability is not currently available.
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Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥68%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met
Application
Amyloid β (Aβ) refers to peptides derived from Amyloid precursor protein that vary in length from 36-43 amino acids. Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer′s disease and neurodegeneration.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Wah Chin Boon et al.
Behavioural brain research, 209(1), 27-35 (2010-01-21)
The aim of this study was to characterize APPC100.V717F transgenic (TgC100.V717F) mice which over-express a mutant C100 fragment of the amyloid precursor protein. The mice were compared to TgC100 wild type mice (TgC100.WT) and non-transgenic controls at 4-9 and 16-22
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