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S7129

Sigma-Aldrich

O-Succinyl-L-homoserine

≥98.0% (TLC), suitable for ligand binding assays

Synonym(s):

L-Homoserine 4-(hydrogen butanedioate)

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About This Item

Empirical Formula (Hill Notation):
C8H13NO6
CAS Number:
1492-23-5
Molecular Weight:
219.19
MDL number:
MFCD00055782
UNSPSC Code:
12352209
PubChem Substance ID:
24899732
NACRES:
NA.26

product name

O-Succinyl-L-homoserine,

Assay

≥98.0% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white

storage temp.

−20°C

SMILES string

N[C@@H](CCOC(=O)CCC(O)=O)C(O)=O

InChI

1S/C8H13NO6/c9-5(8(13)14)3-4-15-7(12)2-1-6(10)11/h5H,1-4,9H2,(H,10,11)(H,13,14)/t5-/m0/s1

InChI key

GNISQJGXJIDKDJ-YFKPBYRVSA-N

Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Ono et al.
Journal of bacteriology, 174(10), 3339-3347 (1992-05-01)
A DNA fragment containing the Saccharomyces cerevisiae CYS3 (CYI1) gene was cloned. The clone had a single open reading frame of 1,182 bp (394 amino acid residues). By comparison of the deduced amino acid sequence with the N-terminal amino acid
P Brzović et al.
Biochemistry, 29(2), 442-451 (1990-01-16)
Cystathionine gamma-synthase catalyzes a pyridoxal phosphate dependent synthesis of cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine via a gamma-replacement reaction. In the absence of L-cysteine, OSHS undergoes an enzyme-catalyzed, gamma-elimination reaction to form succinate, alpha-ketobutyrate, and ammonia. Since elimination of the
M Simon et al.
Journal of bacteriology, 153(1), 558-561 (1983-01-01)
Mutations were found which enable Escherichia coli K-12 to form homocysteine in the absence of cystathionase. The formation of homocysteine in the mutant strains required cystathionine gamma-synthetase, the metB gene product, but bypassed the normal intermediate cystathionine. It is concluded
Stefan Irmler et al.
Applied and environmental microbiology, 74(1), 99-106 (2007-11-13)
Volatile sulfur compounds are key flavor compounds in several cheese types. To better understand the metabolism of sulfur-containing amino acids, which certainly plays a key role in the release of volatile sulfur compounds, we searched the genome database of Lactobacillus
P Vermeij et al.
Journal of bacteriology, 181(18), 5833-5837 (1999-09-11)
Cysteine and methionine biosynthesis was studied in Pseudomonas putida S-313 and Pseudomonas aeruginosa PAO1. Both these organisms used direct sulfhydrylation of O-succinylhomoserine for the synthesis of methionine but also contained substantial levels of O-acetylserine sulfhydrylase (cysteine synthase) activity. The enzymes
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