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P1254

Sigma-Aldrich

Brij® L23

suitable for Stein-Moore chromatography

Synonym(s):

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.21

description

non-ionic

Quality Level

form

solid

mol wt

micellar avg mol wt 48,000
estimated mol wt 1198

aggregation number

20-40

CMC

91 μM

transition temp

cloud point >100 °C

HLB

16.9

suitability

suitable for Stein-Moore chromatography

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

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Application

Non-ionic detergent. Useful for the extraction of membrane proteins. Typically used in the range of 0.1-1%.

Legal Information

Brij is a registered trademark of Croda International PLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

>300.2 °F - open cup

Flash Point(C)

> 149 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Tobimatsu et al.
Archives of biochemistry and biophysics, 347(1), 132-140 (1997-11-05)
Recombinant adenosylcobalamin-dependent diol dehydratase of Klebsiella oxytoca overexpressed in Escherichia coli was purified to homogeneity. The enzyme has a low solubility and was extracted from the crude membrane fraction with 1% Brij 35 in a high recovery. Subsequent chromatography on
K Yamamoto et al.
Biochimica et biophysica acta, 790(3), 208-218 (1984-11-09)
Two forms of an acid proteinase have been purified from human erythrocyte membranes by a simple method involving selective extraction with 0.5% Brij 35, affinity chromatography on pepstatin A-Sepharose 4B, and chromatography on Sephacryl S-200 and DEAE-Sephadex G-100. One species
Jun Koizumi et al.
AJR. American journal of roentgenology, 199(1), 200-207 (2012-06-27)
Balloon-occluded retrograde transvenous obliteration has been traditionally based on liquid sclerotherapy. However, overdose and systemic spillage of liquid sclerosant can cause severe complications, such as hemolysis, which lead to hemoglobinuria, allergy, acute respiratory distress syndrome, and other disorders. The purpose
Jacomina W van den Esschert et al.
Annals of surgery, 255(2), 311-318 (2012-01-14)
To compare the safety and hypertrophy response after portal vein embolization (PVE) using 2 absorbable and 3 permanent embolization materials. Portal vein embolization is used to increase future remnant liver volume preoperatively. Application of temporary, absorbable embolization materials could be
N Shadid et al.
The British journal of surgery, 99(8), 1062-1070 (2012-05-26)
New minimally invasive treatment modalities, such as ultrasound-guided foam sclerotherapy (UGFS), are becoming more popular. In a multicentre randomized controlled non-inferiority trial, the effectiveness and costs of UGFS and surgery for treatment of the incompetent great saphenous vein (GSV) were

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