93285

2,4,6-Tris(2-pyridyl)-s-triazine

for spectrophotometric det. of Fe, ≥99.0% (HPLC)

• Synonym(s): 2,4,6-Tri(2-pyridyl)-s-triazine, TPTZ
• Empirical Formula (Hill Notation): C₁₈H₁₂N₆
• CAS Number: 3682-35-7
• Molecular Weight: 312.33
• Beilstein: 282581
• EC Number: 222-965-9
• MDL number: MFCD00006045
• UNSPSC Code: 12000000
• PubChem Substance ID: 329770219
• NACRES: NA.21

Properties

• Quality Level: 200
• Assay: ≥99.0% (HPLC)
• form: lumps
• quality: for spectrophotometric det. of Fe
• technique(s): UV/Vis spectroscopy: suitable
• loss: ≤0.1 wt. % loss on drying
• mp: 247-249 °C (lit.); 248-252 °C
• solubility: methanol: 100 mg/mL, clear to slightly hazy
• cation traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤100 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: c1ccc(nc1)-c2nc(nc(n2)-c3ccccn3)-c4ccccn4
• InChI: 1S/C18H12N6/c1-4-10-19-13(7-1)16-22-17(14-8-2-5-11-20-14)24-18(23-16)15-9-3-6-12-21-15/h1-12H
• InChI key: KMVWNDHKTPHDMT-UHFFFAOYSA-N

Description

General description

2,4,6-Tris(2-pyridyl)-s-triazine is a Case and Koft compound generally used in determination of iron in a colorimetric analysis.

Application

• Fe(II/III) and Mn(II) complexes based on 2,4,6-tris(2-pyridyl)-triazine: synthesis, structures, magnetic and biological properties.: This research explores the synthesis and structural characterization of iron and manganese complexes with 2,4,6-Tris(2-pyridyl)-s-triazine. The study highlights the compound′s role in forming complexes with unique magnetic and biological properties, making it suitable for applications in materials science and biochemistry (Baca et al., 2022).


• Development of spray-dried N-acetylcysteine dry powder for inhalation.: The article discusses the formulation of a spray-dried powder using 2,4,6-Tris(2-pyridyl)-s-triazine to improve drug delivery in pulmonary systems. This technique enhances the stability and bioavailability of the drug, demonstrating the compound′s versatility in pharmaceutical applications (Ricci et al., 2023).


• Determination of Antioxidant, Anti-Alzheimer, Antidiabetic, Antiglaucoma and Antimicrobial Effects of Zivzik Pomegranate (Punica granatum)-A Chemical Profiling by LC-MS/MS.: This study uses 2,4,6-Tris(2-pyridyl)-s-triazine in the chemical profiling of pomegranate extracts, assessing their potential in treating various diseases. The results underscore the compound′s role in enhancing LC-MS/MS analysis for detecting bioactive compounds in natural products (Gulcin et al., 2023).


• Photoprotection and Antiaging Activity of Extracts from Honeybush (Cyclopia sp.)-In Vitro Wound Healing and Inhibition of the Skin Extracellular Matrix Enzymes: Tyrosinase, Collagenase, Elastase and Hyaluronidase.: In this research, 2,4,6-Tris(2-pyridyl)-s-triazine is used to study the effects of Honeybush extracts on skin health. The compound′s utility in dermatological research and its effectiveness in enhancing analytical methods for studying pharmacological activities are demonstrated (Ochocka et al., 2023).


• Comprehensive Phytochemical Content by LC/MS/MS and Anticholinergic, Antiglaucoma, Antiepilepsy, and Antioxidant Activity of Apilarnil (Drone Larvae).: This paper discusses the use of 2,4,6-Tris(2-pyridyl)-s-triazine in the LC/MS/MS analysis of drone larvae extracts, evaluating their potential pharmacological activities. The study highlights the compound′s critical role in enhancing the sensitivity and specificity of mass spectrometric methods (Gülçin et al., 2023).

Other Notes

Reagent for the spectrophotometric determination of Fe(II) and of total Fe

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves