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81323

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 5,000, methoxy, hydroxyl

Synonym(s):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether, average Mn 5,000

vapor density

>1 (vs air)

vapor pressure

0.05 mmHg ( 20 °C)

form

flakes
powder or crystals

mol wt

average Mn 5,000

mp

60-64 °C

Ω-end

hydroxyl

α-end

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Application

Poly(ethylene glycol) methyl ether (mPEG) is a hydrophilic polymer that is used to control the flexibility of a composite. mPEG can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.

Other Notes

Polymer used in the polymer-supported liquid synthesis of oligosaccharides

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Yvonne K Girard et al.
PloS one, 8(10), e75345-e75345 (2013-10-23)
The development of a suitable three dimensional (3D) culture system for anticancer drug development remains an unmet need. Despite progress, a simple, rapid, scalable and inexpensive 3D-tumor model that recapitulates in vivo tumorigenesis is lacking. Herein, we report on the
Synthesis and characterization of triblock copolymers of methoxy poly (ethylene glycol) and poly (propylene fumarate)
Behravesh E, et al.
Biomacromolecules, 3(1), 153-158 (2002)
Magnetite nanoparticles stabilized with polymeric bilayer of poly (ethylene glycol) methyl ether-poly (?-caprolactone) copolymers
Meerod S, et al.
Polymer, 49(18), 3950-3956 (2008)
"Methoxy poly (ethylene glycol)-poly (lactide)(MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs"
Dong Y and Feng S-S
Biomaterials, 25(14), 2843-2849 (2004)
Hamed Nosrati et al.
Pharmaceutical development and technology, 24(1), 89-98 (2018-01-09)
In this study, we designed a polymersome system for the controlled release of methotrexate (MTX) as an anticancer drug with the objective of improving the loading efficiency of the drug in polymersomes as well as achievement of an efficient control

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