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17343

Sigma-Aldrich

Bromhexine hydrochloride

≥98.0% (AT)

Synonym(s):

2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride, N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride, Bromohexine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C14H20Br2N2 · HCl
CAS Number:
611-75-6
Molecular Weight:
412.59
Beilstein:
4848376
EC Number:
210-280-8
MDL number:
MFCD00056626
UNSPSC Code:
12352100
PubChem Substance ID:
329751532
NACRES:
NA.22

Quality Level

100

Assay

≥98.0% (AT)

form

powder

functional group

amine
bromo

SMILES string

Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2

InChI

1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H

InChI key

UCDKONUHZNTQPY-UHFFFAOYSA-N

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General description

Bromhexine hydrochloride is a bronchial mucolytic.

Application

Bromhexine hydrochloride was used in the secretion of pancreatic juice of low viscosity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBJ8156V
BCBB8827V
BCBB8827
1342515
1147328

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Tatsuhiro Tsujimoto et al.
Alcoholism, clinical and experimental research, 29(12 Suppl), 272S-276S (2005-12-31)
Abstinence is a prerequisite for the treatment of alcoholic chronic pancreatitis, but there are patients who have repeated attacks because of their inability to abstain and the consequent congestive effects of the continued alcohol intake on pancreatic juice. Bromhexine hydrochloride
Ibrahim El Hachmi et al.
Acta orthopaedica Belgica, 78(5), 694-696 (2012-11-21)
Glomus tumours are benign lesions occurring essentially in the hand, with a predilection for the subungueal area. Even though they have been reported in literature, extradigital localisations of glomus tumours are frequently misdiagnosed; they never lead to bone osteolysis. We
J L Vercher-Conejero et al.
Revista espanola de medicina nuclear, 30(2), 97-100 (2010-06-24)
Splenosis is defined as the heterotopic autotransplantation of splenic tissue because of a ruptured spleen due to trauma or surgery. It is a benign and incidental finding, although imaging tests may sometimes orient toward malignancy simulating renal tumors, abdominal lymphomas
Amit Kumar Aggarwal et al.
Drug development and industrial pharmacy, 38(11), 1319-1327 (2012-01-31)
The aim of the present study was to prepare the amino acid prodrugs of bromhexine hydrochloride to improve its solubility. All the prodrugs were synthesized by first reacting bromhexine with tert-butoxycarbonyl (Boc) protected amino acid and then deprotection was carried
N P Barlo et al.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 27(2), 85-95 (2011-02-16)
Idiopathic pulmonary fibrosis (IPF) is a parenchymal lung disease characterized by progressive interstitial fibrosis. In 2002, the ATS/ERS published new criteria that significantly changed the definition of IPF, resulting in a more homogeneous group of patients. IPF has a poor
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