Skip to Content
Merck
All Photos(1)

Documents

16491

Sigma-Aldrich

Methyl bromopyruvate

technical

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
BrCH2COCOOCH3
CAS Number:
7425-63-0
Molecular Weight:
180.98
Beilstein:
1754888
MDL number:
MFCD01862963
UNSPSC Code:
12352100
PubChem Substance ID:
57647569
NACRES:
NA.22

grade

technical

Assay

≥95.0% (T)

form

liquid

density

1.70 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

COC(=O)C(=O)CBr

InChI

1S/C4H5BrO3/c1-8-4(7)3(6)2-5/h2H2,1H3

InChI key

MQONVZMIFQQQHA-UHFFFAOYSA-N

General description

Methyl bromopyruvate is an inhibitor of carbonic anhydrase.

Application

Methyl bromopyruvate was used in the synthesis of 2-(4-amino-4-carboxybutyl)thiazole-4-carboxylic acid and methyl-1-(bromomethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

257.0 °F - closed cup

Flash Point(C)

125 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Anne Katrine Kehler et al.
Investigative ophthalmology & visual science, 48(10), 4688-4693 (2007-09-28)
Inhibition of carbonic anhydrase in the eye is an important treatment modality for reducing the intraocular pressure in glaucoma. However, evidence suggests that carbonic anhydrase inhibition also exerts a relaxing effect on the vessels in the optic nerve, and it
Further degradation products of cephalosporin C. Isolation and synthesis of 2-(4-amino-4-carboxybutyl)thiazole-4-carboxylic acid.
J D JEFFERY et al.
The Biochemical journal, 75, 216-223 (1960-05-01)
Pinhong Chen et al.
The Journal of organic chemistry, 74(19), 7533-7535 (2009-09-26)
With chemoselective Dieckmann condensation as the key step, the protective-group-free total synthesis of (+/-)-subincanadine F was accomplished in 7 steps from the commercially available tryptamine in 33% overall yield.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service