113360

3,4,5-Trimethoxyphenylacetonitrile

97%

• Synonym(s): 3,4,5-Trimethoxybenzyl cyanide
• Linear Formula: (CH₃O)₃C₆H₂CH₂CN
• CAS Number: 13338-63-1
• Molecular Weight: 207.23
• Beilstein: 2214548
• EC Number: 236-388-5
• MDL number: MFCD00001912
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846877
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• mp: 77-79 °C (lit.)
• SMILES string: COc1cc(CC#N)cc(OC)c1OC
• InChI: 1S/C11H13NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4H2,1-3H3
• InChI key: ACFJNTXCEQCDBX-UHFFFAOYSA-N

Description

General description

3,4,5-Trimethoxyphenylacetonitrile is synthesized by the condensation of 3 : 4 : 5-trimethoxybenzaldehyde with hippuric acid.

Application

3,4,5-Trimethoxyphenylacetonitrile is used as an internal standard during the determination of vancomycin in serum. The method used involved a direct and rapid solvent precipitation of protein.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves