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H2393

Sigma-Aldrich

HEPES sodium salt hydrate

≥99% (titration)

Synonym(s):

N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) hemisodium salt

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About This Item

Linear Formula:
C8H17N2O4SNa
CAS Number:
75277-39-3
Molecular Weight:
260.29
EC Number:
278-169-7
MDL number:
MFCD00150464
UNSPSC Code:
12161700
PubChem Substance ID:
24895161

Assay

≥99% (titration)

form

powder

useful pH range

6.8-8.2

 

7.5

pKa 

7.5

solubility

water: 500 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

O.[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.Na.H2O/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;;/h11H,1-8H2,(H,12,13,14);;1H2/q;+1;/p-1

InChI key

ZNJHFNUEQDVFCJ-UHFFFAOYSA-M

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Tina Vognsen et al.
Biochemical and biophysical research communications, 420(1), 188-192 (2012-03-15)
The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7Å resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised
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Methods in molecular biology (Clifton, N.J.), 814, 283-303 (2011-12-07)
A typical feature of astrocytes is their high level of connexin expression. These membrane proteins constitute the molecular basis of two types of channels: gap junction channels that allow direct cytoplasm-to-cytoplasm communication and hemichannels that provide a pathway for exchanges
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British journal of pharmacology, 166(8), 2402-2416 (2012-03-29)
Artificial buffers such as HEPES are extensively used to control extracellular pH (pH(e) ) to investigate the effect of H(+) ions on GABA(A) receptor function. In neurones cultured from spinal cord dorsal horn (DH), dorsal root ganglia (DRG) and cerebellar
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The oligomerization of Aβ peptide into amyloid fibrils is a hallmark of Alzheimer's disease. Due to its biological relevance, phosphate is the most commonly used buffer system for studying the formation of Aβ and other amyloid fibrils. Investigation into the
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The Analyst, 137(19), 4411-4414 (2012-08-07)
We have developed a quickly responsive, and specific fluorescent assay for the detection of Au(III) on the basis of the formation of gold nanoparticles in the presence of HEPES, which cleave the C-I bond of I-BODIPY 1 to yield the
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