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PVP10

Sigma-Aldrich

Polyvinylpyrrolidone

average mol wt 10,000

Synonym(s):

PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
UNSPSC Code:
12352100
PubChem Substance ID:
24899317
NACRES:
NA.21
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form

powder

Quality Level

200

mol wt

average mol wt 10,000

viscosity number

12-18(lit.)

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinylpyrrolidone (polyvidone, povidone, or PVP) is a synthetic water-soluble polymer consisting of linear 1-vinyl-2-pyrrolidinone groups. It is hygroscopic and readily absorbs up to 40% of water by its weight. It has excellent wetting properties in solution and easily forms films, which makes it suitable for use as a coating additive.[1]PVP can be synthesized from its monomer N-vinylpyrrolidone via free-radical polymerization in the presence of AIBN as an initiator. In chemical industries, PVP is widely used as a surface stabilizer, growth modifier, nanoparticle dispersant, and reducing agent.[2][3]

PVP can serve as a surface stabilizer, nanoparticle dispersant, growth modifier, and reducing agent, depending on the synthetic conditions.[2]

Application

PVP (average mol wt 10,000) can be used as a stabilizing agent in the synthesis of metal nanoparticles to prevent them from agglomeration.[4] PVP is also used in the fabrication of mesoporous silica-polymer hybrid (PVP-aminopropyl-SBA-15 Schiff Base hybrid) for the effective removal of divalent heavy metal cations from wastewater. Grafting of PVP functionalization offers a strong affinity for heavy metal ions because it provides two adsorption sites, one through metal-C-O group interaction and the other through metal-π interaction (the chelation of with Schiff base).

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000401204
0000401205
0000358097
WXBF3919V
WXBF4354V

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Guanghua Luo et al.
International journal of medical sciences, 11(10), 1015-1021 (2014-08-20)
Apolipoprotein M (APOM) has been suggested as a vasculoprotective constituent of high density lipoprotein (HDL), which plays a crucial role behind the mechanism of HDL-mediated anti-atherosclerosis. Previous studies demonstrated that insulin resistance could associate with decreased APOM expressions. In agreement
J Tashkhourian et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 82(1), 25-30 (2011-08-09)
A multicomponent analysis method based on principal component analysis-artificial neural network model (PC-ANN) is proposed for the simultaneous determination of levodopa (LD) and benserazide hydrochloride (BH). The method is based on the reaction of levodopa and benserazide hydrochloride with silver
Handbook of pharmaceutical wet granulation
Pharmaceutical Chemistry Journal, 263-315 (2019)
M A Betiha et al.
Journal of hazardous materials, 397, 122675-122675 (2020-05-22)
The mesoporous silica-polymer hybrid was prepared as an adsorbent for divalent heavy metals (Pb(II), Ni(II), and Cu (II)) from rice husk and polyvinylpyrrolidone (PVP) through three successive steps. The first is the preparation of the mesoporous silica (SBA-15), the second
Adam Healey et al.
Plant methods, 10, 21-21 (2014-07-24)
Next-generation sequencing technologies rely on high quality DNA that is suitable for library preparation followed by sequencing. Some plant species store large amounts of phenolics and polysaccharides within their leaf tissue making genomic DNA extraction difficult. While many DNA extraction
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Questions

1–6 of 6 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What solvents can be used to dissolve Product PVP10, Polyvinylpyrrolidone?

    1 answer

    1. This compound is readily soluble in water.  It has also been reported in the chemicals encyclopedia published by the Royal Society of Chemistry, 12th ed., Entry# 7879 to be soluble in ethanol and chloroform, but practically insoluble in ether.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. How can solutions of Product PVP10, Polyvinylpyrrolidone, be kept?

    1 answer

    1. Sterile solutions can probably be kept at room temperature for several months.

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  6. What is the K value in the specification of Product PVP10, Polyvinylpyrrolidone, and how is it determined?

    1 answer

    1. Polyvinylpyrrolidone (PVP) is characterized by its K value, a dimensionless value which is a function of the average molecular weight, the degree of polymerization, and the intrinsic viscosity.  It is calculated from dilute solution viscosity measurements.  log (Ns/No)/C = (75 Ko x Ko)/(1 + 1.5 Ko C) + Ko where Ns = viscosity of the solution, No = viscosity of the solvent and C = concentration in grams per 100 ml of solution. K = 1000 x Ko. The larger the K value for a material, the higher the viscosity.

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