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Supelco

Bacitracin A

VETRANAL®, analytical standard, main stereoisomer ~50 %

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About This Item

Empirical Formula (Hill Notation):
C66H103N17O16S
Molecular Weight:
1422.69
EC Number:
UNSPSC Code:
41116107
PubChem Substance ID:
E Number:
E700
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

composition

main stereoisomer, ~50%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)C(NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

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General description

Bacitracin is a polypeptide antibiotic produced by strains of Bacillus subtilis and Bacillus licheniformis. Bacitracin A is a commercially produced, major microbiologically active component of bacitracin.

Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quantitative high-pressure liquid chromatographic analysis of bacitracin, a polypeptide antibiotic.
Tsuji K, et al.
Journal of Chromatography A, 99(4), 597- 608 (1974)
M M Siegel et al.
Biological mass spectrometry, 23(4), 186-204 (1994-04-01)
The bacitracin antibiotic complex consists principally of bacitracin A, a peptide antibiotic containing seven amino acid residues in a ring and five amino acid residues in a blocked side chain, together with a mixture of minor components presumably related but
L W Tetler et al.
Biological mass spectrometry, 22(12), 712-720 (1993-12-01)
Bacitracin is a mixture of polypeptide antibiotics produced by the action of Bacillus subtilis and Bacillus licheniformis. The mixture has previously been shown to contain at least ten components, of which only the major component, Bacitracin A, and its oxidized
Walter Mancino et al.
Microorganisms, 7(12) (2019-12-08)
Specific members of the genus Bifidobacterium are among the first colonizers of the human/animal gut, where they act as important intestinal commensals associated with host health. As part of the gut microbiota, bifidobacteria may be exposed to antibiotics, used in
Mukundan Ragavan et al.
Analytical chemistry, 83(15), 6054-6059 (2011-06-10)
Hyperpolarization of nuclear spins through techniques such as dynamic nuclear polarization (DNP) can greatly increase the signal-to-noise ratio in NMR measurements, thus eliminating the need for signal averaging. This enables the study of many dynamic processes which would otherwise not

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