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A28651

Sigma-Aldrich

Alloxazine

96%

Synonym(s):

Benzo[g]pteridine-2,4(1H,3H)-dione, Isoalloxazine

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About This Item

Empirical Formula (Hill Notation):
C10H6N4O2
CAS Number:
490-59-5
Molecular Weight:
214.18
EC Number:
207-714-3
MDL number:
MFCD00005020
UNSPSC Code:
12352100
PubChem Substance ID:
24890699
NACRES:
NA.22

Quality Level

100

Assay

96%

form

powder

SMILES string

O=C1NC(=O)c2nc3ccccc3nc2N1

InChI

1S/C10H6N4O2/c15-9-7-8(13-10(16)14-9)12-6-4-2-1-3-5(6)11-7/h1-4H,(H2,12,13,14,15,16)

InChI key

HAUGRYOERYOXHX-UHFFFAOYSA-N

Gene Information

human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136)

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000209733
0000219247
0000174508
MKCC6931
05321DE

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Sammeta V Raju et al.
PloS one, 7(3), e32112-e32112 (2012-03-24)
Alcohol abuse is associated with increased lung infections. Molecular understanding of the underlying mechanisms is not complete. Airway epithelial ion transport regulates the homeostasis of airway surface liquid, essential for airway mucosal immunity and lung host defense. Here, air-liquid interface
Allen M Orville et al.
Biochemistry, 48(4), 720-728 (2009-01-13)
Flavin C4a-OO(H) and C4a-OH adducts are critical intermediates proposed in many flavoenzyme reaction mechanisms, but they are rarely detected even by rapid transient kinetics methods. We observe a trapped flavin C4a-OH or C4a-OO(H) adduct by single-crystal spectroscopic methods and in
Tzong-Yuan Lin et al.
The Journal of biological chemistry, 287(45), 38338-38346 (2012-09-21)
The three-component toluene dioxygenase system consists of an FAD-containing reductase, a Rieske-type [2Fe-2S] ferredoxin, and a Rieske-type dioxygenase. The task of the FAD-containing reductase is to shuttle electrons from NADH to the ferredoxin, a reaction the enzyme has to catalyze
Limor Radoszkowicz et al.
Physical chemistry chemical physics : PCCP, 13(25), 12058-12066 (2011-06-01)
Time-resolved fluorescence decay of flavin adenine dinucleotide (FAD) was studied at room temperature in water and water-methanol mixtures by a fluorescence upconversion technique. The observations were focused on the most initial decay phase (200 ps), before the residual fluorescence assumes
Amanda B Witte et al.
Biomacromolecules, 13(2), 507-516 (2011-12-24)
The present study describes the biophysical characterization of generation-five poly(amidoamine) (PAMAM) dendrimers conjugated with riboflavin (RF) as a cancer-targeting platform. Two new series of dendrimers were designed, each presenting the riboflavin ligand attached at a different site (isoalloxazine at N-3
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