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Sigma-Aldrich

2-Hydroxy-2-methylpropiophenone

97%

Synonym(s):

1-Hydroxy-1-methylethyl phenyl ketone, 1-Phenyl-2-methyl-2-hydroxypropanone, 2-Hydroxy-2-methyl-1-phenyl-1-propanone, 2-Methyl-3-phenyl-3-oxopropan-2-ol

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About This Item

Linear Formula:
C6H5COC(CH3)2OH
CAS Number:
7473-98-5
Molecular Weight:
164.20
EC Number:
231-272-0
MDL number:
MFCD00040710
UNSPSC Code:
12162002
PubChem Substance ID:
24865322
NACRES:
NA.23
Pricing and availability is not currently available.

Quality Level

200

Assay

97%

form

liquid

refractive index

n20/D 1.533 (lit.)

bp

102-103 °C/4 mmHg (lit.)

density

1.077 g/mL at 25 °C (lit.)

SMILES string

CC(C)(O)C(=O)c1ccccc1

InChI

1S/C10H12O2/c1-10(2,12)9(11)8-6-4-3-5-7-8/h3-7,12H,1-2H3

InChI key

XMLYCEVDHLAQEL-UHFFFAOYSA-N

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General description

2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.[1][2][3]

Application

  • Photochemical Thiol-Ene “Click” Chemistry: The study utilized 2-hydroxy-2-methylpropiophenone for the synthesis of highly functional polyols by photochemical thiol-ene “click” chemistry (M Ionescu, A Garcia-Comer, T Spidel, 2023).
  • Development of Water-Soluble Type I Photoinitiators: This study focused on the development of new water-soluble type I photoinitiators for hydrogel synthesis using 2-hydroxy-2-methylpropiophenone, enhancing the understanding of photopolymerization processes (B Aubry, F Dumur, M Lansalot, E Bourgeat-Lami, 2022).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

251.6 °F - closed cup

Flash Point(C)

122 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000408730
0000330340
SHBS1186
0000408730
MKCV7891

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Anirudha Banerjee et al.
Science advances, 5(8), eaax1893-eaax1893 (2019-08-28)
Structures and particles that slowly release solute into solution can attract or repel other particles in suspension via diffusiophoresis, a process we termed "soluto-inertial (SI) interactions." These SI interactions involve "beacons" that establish and sustain nonequilibrium solute fluxes over long
Ana-Irina Cocarta et al.
Materials science & engineering. C, Materials for biological applications, 103, 109799-109799 (2019-07-28)
Retinoblastoma (Rb) is the most common primary malignant intraocular tumor in children which develops from the retinal stem cells. Systemic chemotherapy is the typical therapeutic treatment and though most children survive Rb, they often lose their vision, or the eye
UV-Radiation curing of waterbased urethane-acrylate coatings
Masson F, et al.
Progress in Organic Coatings, 39(2-4), 115-126 (2000)
Photopatternable conductive PDMS materials for microfabrication
Cong H and Pan T
Advances in Functional Materials, 18(13), 1912-1921 (2008)
Martin F Haase et al.
Nature communications, 8(1), 1234-1234 (2017-11-02)
The decoration of porous membranes with a dense layer of nanoparticles imparts useful functionality and can enhance membrane separation and anti-fouling properties. However, manufacturing of nanoparticle-coated membranes requires multiple steps and tedious processing. Here, we introduce a facile single-step method
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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