279072

Cyproheptadine hydrochloride sesquihydrate

99%

• Synonym(s): 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidine hydrochloride hydrate
• Empirical Formula (Hill Notation): C₂₁H₂₁N · HCl · 1.5H₂O
• CAS Number: 41354-29-4
• Molecular Weight: 350.88
• EC Number: 213-535-1
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856848
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• mp: 165 °C (dec.) (lit.)
• solubility: 1 M NH4OH: soluble 25 mg/mL, clear, colorless to faintly yellow
• SMILES string: O.O.O.Cl.CN1CCC(\CC1)=C2\c3ccccc3C=Cc4ccccc24.CN5CCC(\CC5)=C6\c7ccccc7C=Cc8ccccc68
• InChI: 1S/2C21H21N.ClH.3H2O/c2*1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;;;;/h2*2-11H,12-15H2,1H3;1H;3*1H2
• InChI key: PXCSXCDWTUPVIM-UHFFFAOYSA-N

Description

General description

Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine. It induced preventive effect against the development of pergolide-induced valvulopathy in a rat model.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves