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243213

Sigma-Aldrich

Carnauba wax No. 1 yellow

refined

Synonym(s):

Brazil wax

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

form

powder

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General description

Carnauba wax No.1 yellow(CW) is an ester based wax that can be extracted from palm leaves. The composition of this wax contains aliphatic esters, ω-hydroxy esters and unsaturated alcohols. It can be used as a glossing agent in a variety of pharmaceutical products.

Application

CW may be used as a hydrophobic excipient which can be used to modify the kinetics of polymeric gel in a drug releasing system. It can be used in dry polymeric coatings which can increase the crystallization and improve the stability of amorphous solid drug formulations. It may also be used as a component of lipids which can be used to tune and improve the flowability and designing of solid drugs.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Methods of studying aging and stabilization of spray-congealed solid dispersions with carnauba wax. 1. Microcalorimetric investigation.
Em?s M and Nyqvist H
International Journal of Pharmaceutics, 197(1-2), 117-127 (2000)
Carnauba wax as a promising excipient in melt granulation targeting the preparation of mini-tablets for sustained release of highly soluble drugs.
Nart V, et al.
Materials Science and Engineering, C, 70(6), 250-257 (2017)
Enhanced physical stability of amorphous drug formulations via dry polymer coating.
Capece M and Dave R
Journal of Pharmaceutical Sciences, 104(6), 2076-2084 (2015)
Effect of hydrophobic inclusions on polymer swelling kinetics studied by magnetic resonance imaging.
Gajdosova M, et al
International Journal of Pharmaceutics, 500(1-2), 136-143 (2016)
Allergic contact dermatitis to propolis and carnauba wax from lip balm and chewable vitamins in a child.
Sharon E Jacob et al.
Contact dermatitis, 58(4), 242-243 (2008-03-21)

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