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123188

Sigma-Aldrich

5-Aminovaleric acid

97%, for peptide synthesis

Synonym(s):

5-AVA, 5-Aminopentanoic acid, Homopiperidinic acid

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About This Item

Linear Formula:
NH2(CH2)4CO2H
CAS Number:
Molecular Weight:
117.15
Beilstein:
906833
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

product name

5-Aminovaleric acid, 97%

Quality Level

Assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

158-161 °C (lit.)

application(s)

peptide synthesis

SMILES string

NCCCCC(O)=O

InChI

1S/C5H11NO2/c6-4-2-1-3-5(7)8/h1-4,6H2,(H,7,8)

InChI key

JJMDCOVWQOJGCB-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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Application

5-Aminovaleric acid (5-AVA) is used:
  • In the preparation of (5-AVA)x(MA)1-xPbI3, a perovskite for fabricating printable mesoscopic perovskite solar cell.
  • As a spacer in the synthesis of rhenium and technetium-99m labeled insulin.
  • To synthesize dipeptides that self-assemble to form nanotubes in the solid state as well as in solution over a wide range of pH.
  • As a starting material in the total synthesis of an alkaloid, lycoposerramine Z.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis and characterization of rhenium and technetium-99m labeled insulin.
Sundararajan C, et al.
Journal of Medicinal Chemistry, 53(6), 2612-2621 (2010)
A hole-conductor?free, fully printable mesoscopic perovskite solar cell with high stability.
Mei A, et al.
Science, 345(6194), 295-298 (2014)
Ariel Kwaka et al.
Molecular pharmacology, 94(5), 1289-1297 (2018-09-09)
Nematodes exhibit a vast array of cys-loop ligand-gated ion channels with unique pharmacologic characteristics. However, many of the structural components that govern the binding of various ligands are unknown. The nematode cys-loop GABA receptor uncoordinated 49 (UNC-49) is an important
Dipeptide Nanotubes, with N-Terminally Located ω-Amino Acid Residues, That are Stable Proteolytically, Thermally, and Over a Wide Range of pH.
Guha S, et al.
Chemistry of Materials, 20(6), 2282-2290 (2008)
Sylvain Poujol et al.
Clinical chemistry, 49(11), 1900-1908 (2003-10-28)
We developed gradient HPLC methods for quantification of the antimitotic drug irinotecan (CPT-11) and its four metabolites, SN-38, SN-38 G, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]-carbonyloxycamptothecin (APC), and 7-ethyl-10-[4amino-1-piperidino]-carbonyloxycamptothecin (NPC), as the sum of the lactone and carboxylate forms, in human plasma and saliva.

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