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122505

Sigma-Aldrich

2,3-Dihydroxypyridine

95%

Synonym(s):

2,3-Pyridinediol

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About This Item

Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
Molecular Weight:
111.10
Beilstein:
109848
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

mp

245 °C (dec.) (lit.)

SMILES string

Oc1cccnc1O

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

InChI key

GGOZGYRTNQBSSA-UHFFFAOYSA-N

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Application

2,3-Dihydroxypyridine(DHP) was used in the synthesis of DHP loaded amberlite XAD-2 via azo coupler. It was used in the synthesis of new macromolecular chelators by loading DHP on cellulose via linkers -NH-CH2-CH2-NH-SO2-C6H4-N=N- and -SO2-C6H4-N=N.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Lei Wang et al.
European journal of medicinal chemistry, 156, 652-665 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encoded enzymatic function not targeted by current drugs. Although a few chemotypes have been reported to inhibit HIV RNase H in biochemical assays, their
Jayakanth Kankanala et al.
European journal of medicinal chemistry, 141, 149-161 (2017-10-17)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral
Lei Wang et al.
European journal of medicinal chemistry, 156, 680-691 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl
R J Jones et al.
Australian veterinary journal, 63(8), 259-262 (1986-08-01)
Cattle and goats in Australia lack the ability to totally degrade 3-hydroxy-4(1H)-pyridone, also known as 3,4-dihydroxy pyridine (3,4 DHP), the ruminal metabolite of mimosine, a toxic aminoacid present in the leguminous shrub Leucaena leucocephala. Ruminants in Hawaii have this capacity
James M Harrington et al.
Inorganic chemistry, 49(18), 8208-8221 (2010-08-19)
The synthesis of a novel class of exocyclic bis- and tris-3,2-hydroxypyridinone (HOPO) chelators built on N(2) and N(3) aza-macrocyclic scaffolds and the thermodynamic solution characterization of their complexes with Fe(III) are described. The chelators for this study were prepared by

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