WH0009189M1
Monoclonal Anti-ZBED1 antibody produced in mouse
clone 5G1, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-ALTE, Anti-KIAA0785, Anti-TRAMP, Anti-zinc finger, BED-type containing 1
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All Photos(5)
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5G1, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL
isotype
IgG2aκ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ZBED1(9189)
General description
Zinc finger, BED-type containing 1 (ZBED1), also known as DNA replication-related element-binding factor (DREF), is encoded by the single-exon gene mapped to Xp/Yp PAR region that has a functional homolog on the Y chromosome and escapes X-inactivation.
Immunogen
ZBED1 (NP_004720, 3 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKP
Sequence
NKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKP
Biochem/physiol Actions
Zinc finger, BED-type containing 1 (ZBED1) function as a crucial transcription factor for cell proliferation, and is implicated in cell cycle-dependent regulation of a number of ribosomal protein (RP) genes. The encoded protein has been suggested to be involved in the transposition of other transposable elements.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Simone Johansen et al.
Genes, 13(1) (2022-01-22)
The transcription factor ZBED1 is highly expressed in trophoblast cells, but its functions in the processes of trophoblast and placental biology remain elusive. Here, we characterized the role of ZBED1 in trophoblast cell differentiation using an in vitro BeWo cell
Sofie Traynor et al.
Nucleic acids research, 47(13), 6668-6684 (2019-05-23)
Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes
A Helena Mangs et al.
Current genomics, 8(2), 129-136 (2008-07-29)
The pseudoautosomal regions (PAR1 and PAR2) of the human X and Y chromosomes pair and recombine during meiosis. Thus genes in this region are not inherited in a strictly sex-linked fashion. PAR1 is located at the terminal region of the
T Esposito et al.
Human molecular genetics, 8(1), 61-67 (1999-01-15)
We report the cloning of a novel gene, called Tramp, in the Xp/Yp PAR region that has a functional homologue on the Y chromosome and escapes X-inactivation. This gene encodes, within a single exon, a putative protein that has amino
Daisuke Yamashita et al.
Molecular and cellular biology, 27(6), 2003-2013 (2007-01-16)
Although ribosomal proteins (RPs) are essential cellular constituents in all living organisms, mechanisms underlying regulation of their gene expression in mammals remain unclear. We have established that 22 out of 79 human RP genes contain sequences similar to the human
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