T0892

Interleukin-2 from rat

from rat, suitable for cell culture

• Synonym(s): rIL-2, IL-2, T-Cell growth factor, IL-2
• CAS Number: 95568-40-4
• MDL number: MFCD00131401
• UNSPSC Code: 12352200

Properties

• biological source: rat
• form: solid
• potency: 0.2-2.5 units/mL
• storage condition: avoid repeated freeze/thaw cycles
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• UniProt accession no.: P04351
• storage temp.: 2-8°C
• Gene Information: rat ... Il2(116562)

Description

Biochem/physiol Actions

Interleukin-2 is an immunomodulatory factor produced by certain subsets of T lymphocytes. This lympho­kine promotes long term growth of activated T cells and related cell types. Interleukin-2 plays a role in the activation and proliferation of NK cells, induces γ-inter­feron and B cell growth factor secretion, and modulates the expression of the IL-2 receptor.

Unit Definition

One unit is the amount required to induce half-maximal incorporation of ³H-thymidine into IL-2-dependent cytolytic T cell lymphocytes.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 1 mg bovine serum albumin

Preparation Note

Purified from a conditioned medium of a rat splenocyte culture stimulated by concanavalin A.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves