T0386
3,3′,5-Triiodothyropropionic acid
98-99%
Synonym(s):
3-(4-[4-Hydroxy-3-iodophenoxy]-3,5-diiodophenyl)propanoic acid
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About This Item
Empirical Formula (Hill Notation):
C15H11I3O4
CAS Number:
Molecular Weight:
635.96
MDL number:
UNSPSC Code:
12352200
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Assay
98-99%
storage temp.
−20°C
SMILES string
OC(=O)CCc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
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S Naidoo
Analytical biochemistry, 91(2), 543-547 (1978-12-01)
A thin-layer chromatographic method is described for the separation of the acetic and propionic acid analogs of thyroxine and triiodothyronine, which are inseparable by currently available methods. The separation is achieved on silica gel H in a solvent system consisting
T Takeda et al.
The Journal of clinical endocrinology and metabolism, 80(7), 2033-2040 (1995-07-01)
3,5,3,'-Triiodothyroacetic acid (Triac) has been used in therapy of resistance to thyroid hormone on an empirical basis and appears beneficial in some studies. We observed that the T3 analogs, Triac and 3,5,3'-triiodothyropropionic acid (Triprop), have a higher affinity for the
Structure-specific effects of thyroxine analogs on human liver 3 alpha-hydroxysteroid dehydrogenase.
T Yamamoto et al.
Journal of biochemistry, 128(1), 121-128 (2000-07-06)
The NADP(H)-linked oxidoreductase activity of a major isozyme of human liver 3 alpha-hydroxysteroid dehydrogenase was activated 5-, 4-, and 2-fold by D-thyroxine (T(4)), L-T(4) and DL-3,3', 5'-triiodothyronine (reverse T(3)), respectively. Kinetic analysis of the activation indicated that D-T(4), L-T(4), and
S B Hoath et al.
American journal of diseases of children (1960), 138(3), 251-253 (1984-03-01)
We have shown a positive correlation between the epidermal growth factor concentration in neonatal mouse skin and prior treatment with thyroxine (T4) or triiodothyronine (T3). The results of the present study indicate similar activity of other levorotatory iodothyronine analogues and
V Cody
Endocrine research, 14(2-3), 165-176 (1988-01-01)
The crystal and molecular structures of 3,5,3'-triiodothyropropionic acid (T3P), determined as an N-diethanolamine salt, were carried out and the results are compared with those of other thyroid hormone structures. These data show that T3P has an unusual conformation with the
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