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SML2887

Sigma-Aldrich

Firocoxib

≥98% (HPLC)

Synonym(s):

3-(Cyclopropyl-methoxy)-5,5-Dimethy l-4-(4-methylsulfonyl)phenyl)-5H-furan-2-one, 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one, 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, ML 1785713, Previcox, 3-Cyclopropylmethoxy-4-(4-methanesulfonylphenyl)-5,5-dimethyl-5H-furan-2-one

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5 MG
R 1 598,38
25 MG
R 6 453,30

R 1 598,38

List PriceR 1 631,00
Please contact Customer Service for Availability
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5 MG
R 1 598,38
25 MG
R 6 453,30

About This Item

Empirical Formula (Hill Notation):
C17H20O5S
CAS Number:
189954-96-9
Molecular Weight:
336.40
Beilstein:
8335837
MDL number:
MFCD09837800
UNSPSC Code:
51111800
NACRES:
NA.77

R 1 598,38

List PriceR 1 631,00
Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=S(C1=CC=C(C2=C(OCC3CC3)C(OC2(C)C)=O)C=C1)(C)=O

InChI

1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3

InChI key

FULAPETWGIGNMT-UHFFFAOYSA-N

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Biochem/physiol Actions

Firocoxib is an orally available non-steroidal anti-inflammatory drug (NSAID) that selectively and potently inhibits cyclooxygenase-2-(COX-2). Firocoxib is approved to use in dogs and horses.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Amy K Stuart et al.
Journal of veterinary pharmacology and therapeutics, 42(6), 640-646 (2019-08-23)
Pharmacokinetic (PK) studies of oral firocoxib in large animal species have been limited to horses, preruminating calves, and adult camels. The aim of this study was to describe pharmacokinetics and bioavailability of firocoxib in adult goats. Ten healthy adult goats
Milena M Madry et al.
BMC veterinary research, 12, 84-84 (2016-06-03)
Compared to blood or urine, drugs can be detected for much longer periods in the long hair of horses. The aim of this study was to establish and validate a highly sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method for
Prangtip Phuwapattanachart et al.
Journal of veterinary science, 18(2), 175-182 (2016-08-16)
The postoperative analgesic effects of firocoxib in ovariohysterectomized cats were observed. Twenty-four cats were divided into 3 groups: control (no medicine), firocoxib-1 (1 mg/kg/day) and firocoxib-3 (3 mg/kg/day). Colorado pain scale scores (CPSS), composite pain scores (CPS), and buccal mucosal

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